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urinary bladder transitional carcinoma cell line  (ATCC)


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    ATCC urinary bladder transitional carcinoma cell line
    Urinary Bladder Transitional Carcinoma Cell Line, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 3061 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/urinary bladder transitional carcinoma cell line/product/ATCC
    Average 99 stars, based on 3061 article reviews
    urinary bladder transitional carcinoma cell line - by Bioz Stars, 2026-02
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    human urinary bladder transitional cell carcinoma cell line um-uc-1  (European Collection of Authenticated Cell Cultures)
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    European Collection of Authenticated Cell Cultures human urinary bladder transitional cell carcinoma cell line um-uc-1
    circNCOR1 inhibits LN metastasis of bladder cancer by inhibiting the TGFβ–SMAD signaling pathway. A – C, Representative images ( A ) and quantification of the tube formation ( B ) and Transwell migration ( C ) by HLECs cocultured with UM-UC-3 cells. Scale bars, 100 μm. D, The popliteal LN metastatic rate in the nude mice ( n = 12 per group). E and F, Bioluminescence ( E ) and LN volume ( F ) of popliteal LN metastasis in the nude mice ( n = 12 per group). G, Luciferase activity of the SMAD7 promoter in indicated UM-UC-3 cells. H, qRT-PCR analysis of SMAD7 expression in indicated UM-UC-3 cells. I and J, Western blotting of SMAD7 expression in indicated UM-UC-3 ( I ) and <t>T24</t> ( J ) cells. The statistical difference was assessed by the two-tailed Student t test in B , C , E , and F , and the χ 2 test in D ; and one-way ANOVA followed by Dunnett tests in G and H . Error bars show the SD from three independent experiments. **, P < 0.01.
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    circNCOR1 inhibits LN metastasis of bladder cancer by inhibiting the TGFβ–SMAD signaling pathway. A – C, Representative images ( A ) and quantification of the tube formation ( B ) and Transwell migration ( C ) by HLECs cocultured with UM-UC-3 cells. Scale bars, 100 μm. D, The popliteal LN metastatic rate in the nude mice ( n = 12 per group). E and F, Bioluminescence ( E ) and LN volume ( F ) of popliteal LN metastasis in the nude mice ( n = 12 per group). G, Luciferase activity of the SMAD7 promoter in indicated UM-UC-3 cells. H, qRT-PCR analysis of SMAD7 expression in indicated UM-UC-3 cells. I and J, Western blotting of SMAD7 expression in indicated UM-UC-3 ( I ) and T24 ( J ) cells. The statistical difference was assessed by the two-tailed Student t test in B , C , E , and F , and the χ 2 test in D ; and one-way ANOVA followed by Dunnett tests in G and H . Error bars show the SD from three independent experiments. **, P < 0.01.

    Journal: Cancer Research

    Article Title: Aberrant Nuclear Export of circNCOR1 Underlies SMAD7-Mediated Lymph Node Metastasis of Bladder Cancer

    doi: 10.1158/0008-5472.CAN-21-4349

    Figure Lengend Snippet: circNCOR1 inhibits LN metastasis of bladder cancer by inhibiting the TGFβ–SMAD signaling pathway. A – C, Representative images ( A ) and quantification of the tube formation ( B ) and Transwell migration ( C ) by HLECs cocultured with UM-UC-3 cells. Scale bars, 100 μm. D, The popliteal LN metastatic rate in the nude mice ( n = 12 per group). E and F, Bioluminescence ( E ) and LN volume ( F ) of popliteal LN metastasis in the nude mice ( n = 12 per group). G, Luciferase activity of the SMAD7 promoter in indicated UM-UC-3 cells. H, qRT-PCR analysis of SMAD7 expression in indicated UM-UC-3 cells. I and J, Western blotting of SMAD7 expression in indicated UM-UC-3 ( I ) and T24 ( J ) cells. The statistical difference was assessed by the two-tailed Student t test in B , C , E , and F , and the χ 2 test in D ; and one-way ANOVA followed by Dunnett tests in G and H . Error bars show the SD from three independent experiments. **, P < 0.01.

    Article Snippet: The human urinary bladder transitional cell carcinoma cell lines T24 (RRID: CVCL_0554), UM-UC-3 (RRID: CVCL_1783) were purchased from ATCC, RT112 (RRID: CVCL_1670) was purchased from German Collection of Microorganisms and Cell Cultures GmbH (DSMZ) and UM-UC-1 (RRID: CVCL_2743) was purchased from European Collection of Authenticated Cell Cultures (ECACC).

    Techniques: Migration, Luciferase, Activity Assay, Quantitative RT-PCR, Expressing, Western Blot, Two Tailed Test